Rectal Absorption Enhancement of Oxaprozin Using Solid Dispersion with Polyvinylpyrrolidone.

dissolution rate enhancement of irbesartan using solid dispersion with pegs

Amorphisation of Nifluminic Acid with Polyvinylpyrrolidone Prepared Solid Dispersion to Reach Rapid Drug Release

This paper describes the enhancement of dissolution rate of nifluminic acid by spray dry process, as a solid dispersion method using polyvinylpyrrolidone (PVP C-15) as a water soluble polymer. Using solid dispersions as a well-known principle on an industrial scale, it has to be combined with low-cost and repetable manufacturing method. Therefore, the aim of the authors was the amorphisation of...

dissolution enhancement of glybenclamide by solid dispersion technique

Microspherical Particles of Solid Dispersion of Polyvinylpyrrolidone K29-32 for Inhalation Administration

Inhalation administration is a promising alternative to the invasive drug delivery methods. The particle size required for ideal drug aerosol preparation is between 1 and 3 μm. The application of microspherical particles of solid dispersions enhances bioavailability of poorly soluble drugs due to the solubilization. In the present work, the spray drying process of the production of microspheric...

single-step synthesis of multi-component spirobarbiturates using ionic liquids and synthesis of substituted pyridine filled with catalysts supported on solid substrate

in this thesis, a better reaction conditions for the synthesis of spirobarbiturates catalyzed by task-specific ionic liquid (2-hydroxy-n-(2-hydroxyethyl)-n,n-dimethylethanaminium formate), calcium hypochlorite ca(ocl)2 or n-bromosuccinimide (nbs) in the presence of water at room temperature by ultrasonic technique is provided. the design and synthesis of spirocycles is a challenging task becaus...